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1.
Actas dermo-sifiliogr. (Ed. impr.) ; 114(1): 19-24, jan. 2023. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-214468

RESUMO

Background Although partial onychectomy with chemical matricectomy has been described as the treatment of choice, there is sparse evidence in the literature regarding the use of silver nitrate for matricectomy. Our aim is to describe the effectiveness of silver nitrate for matrix cauterization after partial onychectomy. Methods A prospective observational study was performed on patients with ingrown toenails stage 2–3 who underwent partial onychectomy with silver nitrate chemical matricectomy during 2018–2019 in our institution. All patients were evaluated in the outpatient clinic on the 7th and 30th post-operative day and a telephone evaluation was performed every 6 months after the surgical procedure to date. Results One hundred and twenty-three patients, who underwent 231 partial onychectomies with silver nitrate chemical matricectomy were included, with a median follow-up of 21 months (interquartile range, 12–29). The procedure had an effectiveness of 95.3%, with only 11 recurrences (4.7%) reported so far on follow-up. Postoperative infections were observed in 4 patients (1.7%). Adverse effects, such as pain and postoperative drainage, were irrelevant in most patients. Conclusions Silver nitrate matricectomy after partial onychectomy is an effective and safe alternative for the treatment of ingrown toenail in children, with scarce postoperative morbidity and low recurrence rate (AU)


Antecedentes Aunque la onicectomía parcial con matricectomía química ha sido descrita como tratamiento de elección en los casos de uñas encarnadas en los dedos de los pies, existe escasa evidencia en la literatura en cuanto al uso de nitrato de plata para matricectomía. Nuestro objetivo es describir la efectividad del nitrato de plata para cauterización de la matriz tras onicectomía parcial. Métodos Se realizó un estudio observacional prospectivo en pacientes con uñas encarnadas en los dedos de los pies estadio 2-3, sometidos a onicectomía parcial con matricectomía con nitrato de plata durante los años 2018 y 2019 en nuestra institución. Se evaluó a todos los pacientes en la clínica ambulatoria el 7.° y 30.° días postoperatorios, realizándose una evaluación telefónica cada 6 meses, a contar desde la fecha de la intervención quirúrgica. Resultados Se incluyó a 123 pacientes, a quienes se realizaron 231 onicectomías parciales con matricectomía química con nitrato de plata, con un seguimiento medio de 21 meses (rango intercuartílico: 12-29). El procedimiento tuvo una efectividad del 95,3%, con solo 11 recidivas (4,7%) reportadas hasta el seguimiento. Se observaron infecciones postoperatorias en 4 pacientes (1,7%). Los efectos adversos, tales como dolor y el flujo postoperatorio, fueron irrelevantes en muchos pacientes. Conclusiones La matricectomía con nitrato de plata tras onicectomía parcial es una alternativa efectiva y segura para el tratamiento de las uñas encarnadas en niños, con escasa morbilidad postoperatoria y baja tasa de recidiva (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Nitrato de Prata/uso terapêutico , Unhas Encravadas/terapia , Cauterização/métodos , Resultado do Tratamento , Estudos Prospectivos , Projetos Piloto , Recidiva , Corantes
2.
Actas dermo-sifiliogr. (Ed. impr.) ; 114(1): T19-T24, jan. 2023. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-214469

RESUMO

Antecedentes Aunque la onicectomía parcial con matricectomía química ha sido descrita como tratamiento de elección en los casos de uñas encarnadas en los dedos de los pies, existe escasa evidencia en la literatura en cuanto al uso de nitrato de plata para matricectomía. Nuestro objetivo es describir la efectividad del nitrato de plata para cauterización de la matriz tras onicectomía parcial. Métodos Se realizó un estudio observacional prospectivo en pacientes con uñas encarnadas en los dedos de los pies estadio 2-3, sometidos a onicectomía parcial con matricectomía con nitrato de plata durante los años 2018 y 2019 en nuestra institución. Se evaluó a todos los pacientes en la clínica ambulatoria el 7.° y 30.° días postoperatorios, realizándose una evaluación telefónica cada 6 meses, a contar desde la fecha de la intervención quirúrgica. Resultados Se incluyó a 123 pacientes, a quienes se realizaron 231 onicectomías parciales con matricectomía química con nitrato de plata, con un seguimiento medio de 21 meses (rango intercuartílico: 12-29). El procedimiento tuvo una efectividad del 95,3%, con solo 11 recidivas (4,7%) reportadas hasta el seguimiento. Se observaron infecciones postoperatorias en 4 pacientes (1,7%). Los efectos adversos, tales como dolor y el flujo postoperatorio, fueron irrelevantes en muchos pacientes. Conclusiones La matricectomía con nitrato de plata tras onicectomía parcial es una alternativa efectiva y segura para el tratamiento de las uñas encarnadas en niños, con escasa morbilidad postoperatoria y baja tasa de recidiva (AU)


Background Although partial onychectomy with chemical matricectomy has been described as the treatment of choice, there is sparse evidence in the literature regarding the use of silver nitrate for matricectomy. Our aim is to describe the effectiveness of silver nitrate for matrix cauterization after partial onychectomy. Methods A prospective observational study was performed on patients with ingrown toenails stage 2–3 who underwent partial onychectomy with silver nitrate chemical matricectomy during 2018–2019 in our institution. All patients were evaluated in the outpatient clinic on the 7th and 30th post-operative day and a telephone evaluation was performed every 6 months after the surgical procedure to date. Results One hundred and twenty-three patients, who underwent 231 partial onychectomies with silver nitrate chemical matricectomy were included, with a median follow-up of 21 months (interquartile range, 12–29). The procedure had an effectiveness of 95.3%, with only 11 recurrences (4.7%) reported so far on follow-up. Postoperative infections were observed in 4 patients (1.7%). Adverse effects, such as pain and postoperative drainage, were irrelevant in most patients. Conclusions Silver nitrate matricectomy after partial onychectomy is an effective and safe alternative for the treatment of ingrown toenail in children, with scarce postoperative morbidity and low recurrence rate (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Nitrato de Prata/uso terapêutico , Unhas Encravadas/terapia , Cauterização/métodos , Resultado do Tratamento , Estudos Prospectivos , Projetos Piloto , Recidiva , Corantes
3.
Actas Dermosifiliogr ; 114(1): 19-24, 2023 Jan.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-35905818

RESUMO

BACKGROUND: Although partial onychectomy with chemical matricectomy has been described as the treatment of choice, there is sparse evidence in the literature regarding the use of silver nitrate for matricectomy. Our aim is to describe the effectiveness of silver nitrate for matrix cauterization after partial onychectomy. METHODS: A prospective observational study was performed on patients with ingrown toenails stage 2-3 who underwent partial onychectomy with silver nitrate chemical matricectomy during 2018-2019 in our institution. All patients were evaluated in the outpatient clinic on the 7th and 30th post-operative day and a telephone evaluation was performed every 6 months after the surgical procedure to date. RESULTS: One hundred and twenty-three patients, who underwent 231 partial onychectomies with silver nitrate chemical matricectomy were included, with a median follow-up of 21 months (interquartile range, 12-29). The procedure had an effectiveness of 95.3%, with only 11 recurrences (4.7%) reported so far on follow-up. Postoperative infections were observed in 4 patients (1.7%). Adverse effects, such as pain and postoperative drainage, were irrelevant in most patients. CONCLUSIONS: Silver nitrate matricectomy after partial onychectomy is an effective and safe alternative for the treatment of ingrown toenail in children, with scarce postoperative morbidity and low recurrence rate.


Assuntos
Unhas Encravadas , Unhas , Humanos , Criança , Unhas/cirurgia , Projetos Piloto , Nitrato de Prata/uso terapêutico , Unhas Encravadas/cirurgia , Cauterização/métodos , Recidiva
4.
Actas Dermosifiliogr ; 114(1): T19-T24, 2023 Jan.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-36574519

RESUMO

BACKGROUND: Although partial onychectomy with chemical matricectomy has been described asthe treatment of choice, there is sparse evidence in the literature regarding the use of silvernitrate for matricectomy. Our aim is to describe the effectiveness of silver nitrate for matrixcauterization after partial onychectomy. METHODS: A prospective observational study was performed on patients with ingrown toenailsstage 2-3 who underwent partial onychectomy with silver nitrate chemical matricectomy during 2018-2019 in our institution. All patients were evaluated in the outpatient clinic on the 7th and 30th post-operative day and a telephone evaluation was performed every 6 months afterthe surgical procedure to date. RESULTS: One hundred and twenty-three patients, who underwent 231 partial onychectomies with silver nitrate chemical matricectomy were included, with a median follow-up of 21 months (interquartile range, 12-29). The procedure had an effectiveness of 95.3%, with only 11 recur-rences (4.7%) reported so far on follow-up. Postoperative infections were observed in 4 patients (1.7%). Adverse effects, such as pain and postoperative drainage, were irrelevant in mostpatients. CONCLUSIONS: Silver nitrate matricectomy after partial onychectomy is an effective and safealternative for the treatment of ingrown toenail in children, with scarce postoperative morbidityand low recurrence rate.


Assuntos
Unhas Encravadas , Unhas , Humanos , Criança , Unhas/cirurgia , Projetos Piloto , Nitrato de Prata/uso terapêutico , Unhas Encravadas/cirurgia , Cauterização/métodos , Corantes , Recidiva
5.
Cir Pediatr ; 34(2): 85-89, 2021 Apr 01.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33826261

RESUMO

INTRODUCTION: As a result of the emergence of the SARS-CoV-2 respiratory virus in Wuhan in December 2019, the Spanish Government declared the state of emergency with restrictions such as stay-at-home lockdown. The objective of this study was to analyze emergency activity at a referral pediatric surgery unit in its territory and determine whether surgical pathologies had decreased or not. METHODS: A retrospective study of pediatric patients presenting at the emergency department and referred to the pediatric surgery unit from March 14, 2020 to April 20, 2020 was carried out. The results were compared with those from the same dates of the previous year. Demographic variables, pathologies, and management strategies were studied for each case. The number of patients with abdominal pain requiring surgical assessment was also analyzed. RESULTS: 161 patients were included - 91 from 2019 and 70 from 2020. Of the 2020 patients, 62 (88.6%) underwent surgery and 8 (11.4%) were admitted, whereas in 2019, patient distribution was 67 (73.6%) and 24 (26.4%), which means there were fewer admissions in 2020 (p= 0.018). There were no differences in terms of hours to emergency department consultation - just an increase in the case of appendicular pathologies in the 2020 period, with 24 [23-48] hours vs. 24 [12-30] hours (p =  0.045). CONCLUSION: The current pandemic has not caused emergency surgeries to decrease. It has only increased time to consultation in patients with appendicular pathologies.


INTRODUCCION: A raíz de la aparición del virus respiratorio SARS-CoV-2 en Wuhan en diciembre de 2019, el Gobierno de España decretó el estado de alarma con medidas que han incluido el confinamiento domiciliario. El objetivo de este trabajo es analizar la actividad urgente de un Servicio de Cirugía Pediátrica referente en su Comunidad Autónoma y comprobar si ha existido disminución o no en la patología quirúrgica. METODOS: Estudio retrospectivo de los pacientes pediátricos que acudieron a Urgencias y fueron derivados a Cirugía Pediátrica entre los periodos del 14 de marzo hasta el 20 de abril de 2020, comparándolos con aquellos que acudieron en las mismas fechas del año previo. Se analizaron variables demográficas, la patología y el tipo de manejo en cada caso. Se analizó también el número de pacientes con dolor abdominal que precisaron valoración quirúrgica. RESULTADOS: Se incluyeron 161 pacientes, de los que 91 acudieron en 2019 y 70 acudieron en 2020. De estos últimos, 62 (88,6%) fueron intervenidos y 8 (11,4%) fueron hospitalizados, mientras que en 2019 fueron 67 (73,6%) y 24 (26,4%), respectivamente, observando un menor número de ingresos en 2020 (p=  0,018). El número de horas de evolución hasta la consulta en Urgencias del total de pacientes no demostró diferencias, únicamente existió un aumento en los pacientes con patología apendicular en el periodo de 2020, 24 [23-48] respecto al periodo del año previo 24 [12-30] (p=  0,045). CONCLUSION: La situación actual de pandemia no ha provocado una disminución del número de intervenciones quirúrgicas urgentes. Únicamente aumentó el tiempo hasta la consulta en los pacientes con patología apendicular.


Assuntos
COVID-19/epidemiologia , Serviço Hospitalar de Emergência/estatística & dados numéricos , Pandemias , Pediatria/estatística & dados numéricos , Centro Cirúrgico Hospitalar/estatística & dados numéricos , Dor Abdominal/epidemiologia , Apendicite/epidemiologia , Apendicite/cirurgia , Criança , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Masculino , Estudos Retrospectivos , Centros de Atenção Terciária , Tempo para o Tratamento
6.
Cir. pediátr ; 34(2): 85-89, Abr. 2021. tab
Artigo em Espanhol | IBECS | ID: ibc-216656

RESUMO

Introducción: A raíz de la aparición del virus respiratorio SARS-CoV-2 en Wuhan en diciembre de 2019, el Gobierno de España decretóel estado de alarma con medidas que han incluido el confinamiento do-miciliario. El objetivo de este trabajo es analizar la actividad urgente deun Servicio de Cirugía Pediátrica referente en su Comunidad Autónomay comprobar si ha existido disminución o no en la patología quirúrgica. Métodos: Estudio retrospectivo de los pacientes pediátricos queacudieron a Urgencias y fueron derivados a Cirugía Pediátrica entre losperiodos del 14 de marzo hasta el 20 de abril de 2020, comparándoloscon aquellos que acudieron en las mismas fechas del año previo. Seanalizaron variables demográficas, la patología y el tipo de manejoen cada caso. Se analizó también el número de pacientes con dolorabdominal que precisaron valoración quirúrgica. Resultados: Se incluyeron 161 pacientes, de los que 91 acudieronen 2019 y 70 acudieron en 2020. De estos últimos, 62 (88,6%) fue-ron intervenidos y 8 (11,4%) fueron hospitalizados, mientras que en2019 fueron 67 (73,6%) y 24 (26,4%), respectivamente, observandoun menor número de ingresos en 2020 (p= 0,018). El número de horasde evolución hasta la consulta en Urgencias del total de pacientes nodemostró diferencias, únicamente existió un aumento en los pacientescon patología apendicular en el periodo de 2020, 24 [23-48] respectoal periodo del año previo 24 [12-30] (p= 0,045). Conclusión: La situación actual de pandemia no ha provocadouna disminución del número de intervenciones quirúrgicas urgentes.Únicamente aumentó el tiempo hasta la consulta en los pacientes conpatología apendicular.(AU)


Introduction: As a result of the emergence of the SARS-CoV-2respiratory virus in Wuhan in December 2019, the Spanish Governmentdeclared the state of emergency with restrictions such as stay-at-homelockdown. The objective of this study was to analyze emergency activityat a referral pediatric surgery unit in its territory and determine whethersurgical pathologies had decreased or not. Methods: A retrospective study of pediatric patients presentingat the emergency department and referred to the pediatric surgery unitfrom March 14, 2020 to April 20, 2020 was carried out. The resultswere compared with those from the same dates of the previous year.Demographic variables, pathologies, and management strategies werestudied for each case. The number of patients with abdominal painrequiring surgical assessment was also analyzed. Results: 161 patients were included – 91 from 2019 and 70 from2020. Of the 2020 patients, 62 (88.6%) underwent surgery and 8 (11.4%)were admitted, whereas in 2019, patient distribution was 67 (73.6%)and 24 (26.4%), which means there were fewer admissions in 2020(p= 0.018). There were no differences in terms of hours to emergencydepartment consultation – just an increase in the case of appendicularpathologies in the 2020 period, with 24 [23-48] hours vs. 24 [12-30]hours (p = 0.045). Conclusion: The current pandemic has not caused emergency sur-geries to decrease. It has only increased time to consultation in patientswith appendicular pathologies.(AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Pandemias , Coronavírus Relacionado à Síndrome Respiratória Aguda Grave , Infecções por Coronavirus/epidemiologia , Emergências , Pediatria , Espanha , Cirurgia Geral , Estudos Retrospectivos
7.
Cir Pediatr ; 33(1): 20-24, 2020 Jan 20.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32166919

RESUMO

INTRODUCTION: Overweight and obesity are risk factors for the development of postsurgical complications in acute appendicitis in adults. However, there are few studies that evaluate their effects in pediatric patients. We aim to analyze their influence on the postoperative course of acute appendicitis in children. MATERIAL AND METHODS: A prospective cohort study was performed in patients undergoing surgery for acute appendicitis in 2017-2018, divided into two cohorts according to BMI adjusted to sex and age, following the WHO criteria: exposed cohort (overweight-obese) and non-exposed cohort (normal weight). Clinical follow-up was performed during hospital admission and one month after surgery. Demographic variables, operating time, average hospital stay, and early postoperative complications (wound infection, wound dehiscence, and intra-abdominal abscess) were assessed. RESULTS: A total of 403 patients were included (exposed cohort n=97 and non-exposed cohort n=306), with no differences in sex or age. A longer operating time was observed in the exposed cohort (57.6 ± 22.5 vs. 44.6 ± 18.2 min, p<0.001), with no differences found according to the surgical approach (open surgery or laparoscopic surgery) used. This group also had a higher surgical wound infection rate as compared to the non-exposed cohort (10.3% vs. 4.2%; RR: 1.90; CI: 95% [1.15-3.14], p<0.001), as well as a higher surgical wound dehiscence rate (7.2% vs. 2.3%; RR: 2.16; CI: 95% [1.24-3.76], p<0.001). No differences in the development of intra-abdominal abscesses or in hospital stay were observed. CONCLUSIONS: Obese and overweight children with appendicitis have a higher risk of developing postoperative complications such as wound infection and dehiscence than normal weight patients.


INTRODUCCION: El sobrepeso y la obesidad constituyen factores de riesgo para el desarrollo de complicaciones postquirúrgicas en apendicitis aguda en adultos. Sin embargo, pocos estudios han evaluado sus efectos en pacientes pediátricos. Nuestro objetivo es analizar su influencia en el curso postoperatorio de la apendicitis aguda en niños. MATERIAL Y METODOS: Estudio de cohortes prospectivo realizado en pacientes intervenidos de apendicitis aguda durante 2017-2018, distribuidos en dos cohortes según el IMC ajustado al sexo y edad de cada individuo siguiendo los criterios de la OMS: cohorte expuesta (sobrepeso-obesidad) y no expuesta (normopeso). Se evaluaron variables demográficas, tiempo quirúrgico, estancia media hospitalaria y complicaciones postoperatorias precoces (infección y dehiscencia de herida quirúrgica y absceso intraabdominal). RESULTADOS: Se incluyeron un total de 403 pacientes (cohorte expuesta n= 97 y cohorte no expuesta n= 306) sin diferencias en sexo y edad. La cohorte expuesta presentó un mayor tiempo quirúrgico (57,6 ± 22,5 minutos vs 44,6 ± 18,2 minutos; p<0,001), sin diferencias en cuanto a la técnica quirúrgica realizada (abierta o laparoscópica). Este grupo presentó mayor tasa de infección de herida quirúrgica al compararla con la cohorte no expuesta (10,3% vs 4,2%; RR 1,90 IC95% [1,15-3,14]; p<0,001), así como una mayor tasa de dehiscencia de herida quirúrgica (10,3% vs 4,2%; RR 2,16 IC95% [1,24-3,76]; p<0,001). No se observaron diferencias en el desarrollo de abscesos intraabdominales ni en la estancia media hospitalaria. CONCLUSIONES: El sobrepeso y obesidad infantil constituyen un factor de riesgo para el desarrollo de complicaciones postoperatorias en la apendicitis aguda, como infección y dehiscencia de la herida quirúrgica.


Assuntos
Apendicectomia/métodos , Apendicite/cirurgia , Obesidade Pediátrica/epidemiologia , Complicações Pós-Operatórias/epidemiologia , Adolescente , Criança , Estudos de Coortes , Feminino , Seguimentos , Humanos , Laparoscopia , Tempo de Internação , Masculino , Duração da Cirurgia , Estudos Prospectivos , Infecção da Ferida Cirúrgica/epidemiologia
8.
Cir. pediátr ; 33(1): 20-24, ene. 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-186133

RESUMO

Introducción: El sobrepeso y la obesidad constituyen factores de riesgo para el desarrollo de complicaciones postquirúrgicas en apendicitis aguda en adultos. Sin embargo, pocos estudios han evaluado sus efectos en pacientes pediátricos. Nuestro objetivo es analizar su influencia en el curso postoperatorio de la apendicitis aguda en niños. Material y métodos: Estudio de cohortes prospectivo realizado en pacientes intervenidos de apendicitis aguda durante 2017-2018, distribuidos en dos cohortes según el IMC ajustado al sexo y edad de cada individuo siguiendo los criterios de la OMS: cohorte expuesta (sobrepeso-obesidad) y no expuesta (normopeso). Se evaluaron variables demográficas, tiempo quirúrgico, estancia media hospitalaria y complicaciones postoperatorias precoces (infección y dehiscencia de herida quirúrgica y absceso intraabdominal). Resultados: Se incluyeron un total de 403 pacientes (cohorte expuesta n= 97 y cohorte no expuesta n= 306) sin diferencias en sexo y edad. La cohorte expuesta presentó un mayor tiempo quirúrgico (57,6 ± 22,5 minutos vs 44,6 ± 18,2 minutos; p< 0,001), sin diferencias en cuanto a la técnica quirúrgica realizada (abierta o laparoscópica). Este grupo presentó mayor tasa de infección de herida quirúrgica al compararla con la cohorte no expuesta (10,3% vs 4,2%; RR 1,90 IC95% [1,15-3,14]; p< 0,001), así como una mayor tasa de dehiscencia de herida quirúrgica (10,3% vs 4,2%; RR 2,16 IC95% [1,24-3,76]; p< 0,001). No se observaron diferencias en el desarrollo de abscesos intraabdominales ni en la estancia media hospitalaria. Conclusiones: El sobrepeso y obesidad infantil constituyen un factor de riesgo para el desarrollo de complicaciones postoperatorias en la apendicitis aguda, como infección y dehiscencia de la herida quirúrgica


Introduction: Overweight and obesity are risk factors for the de-velopment of postsurgical complications in acute appendicitis in adults. However, there are few studies that evaluate their effects in pediatric patients. We aim to analyze their influence on the postoperative course of acute appendicitis in children. Materials and methods: A prospective cohort study was performed in patients undergoing surgery for acute appendicitis in 2017-2018, divided into two cohorts according to BMI adjusted to sex and age, following the WHO criteria: exposed cohort (overweight-obese) and non-exposed cohort (normal weight). Clinical follow-up was performed during hospital admission and one month after surgery. Demographic variables, operating time, average hospital stay, and early postoperative complications (wound infection, wound dehiscence, and intra-abdominal abscess) were assessed. Results: A total of 403 patients were included (exposed cohort n=97 and non-exposed cohort n=306), with no differences in sex or age. A longer operating time was observed in the exposed cohort (57.6 ± 22.5 vs. 44.6 ± 18.2min, p<0.001), with no differences found according to the surgical approach (open surgery or laparoscopic surgery) used. This group also had a higher surgical wound infection rate as compared to the non-exposed cohort (10.3% vs. 4.2%; RR: 1.90; CI: 95% [1.15-3.14], p<0.001), as well as a higher surgical wound dehiscence rate (7.2% vs. 2.3%; RR: 2.16; CI: 95% [1.24-3.76], p<0.001). No differences in the development of intra-abdominal abscesses or in hospital stay were observed. Conclusions: Obese and overweight children with appendicitis have a higher risk of developing postoperative complications such as wound infection and dehiscence than normal weight patients


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Sobrepeso , Obesidade Pediátrica/complicações , Apendicite/cirurgia , Estudos de Coortes , Fatores de Risco , Complicações Pós-Operatórias/cirurgia , Infecção da Ferida Cirúrgica , Estudos Prospectivos , Deiscência da Ferida Operatória , Abscesso Abdominal
9.
Cir Pediatr ; 32(4): 185-189, 2019 10 01.
Artigo em Espanhol | MEDLINE | ID: mdl-31626403

RESUMO

AIM OF THE STUDY: The neutrophil-to-lymphocyte ratio (NLR) has been postulated as an inflammatory marker in several abdominal pathologies such as acute appendicitis (AA). However, there are few studies that determine its association with the degree of severity of AA. This is the first study that analyzes the usefulness of NLR as a predictor of peritonitis in children with AA. METHODS: Retrospective observational study in patients treated of AA during the years 2017 and 2018. They were divided into two groups according to the intraoperative diagnosis (uncomplicated AA and AA with peritonitis). Demographic and analytical variables were analyzed. The NLR was defined as the quotient between the absolute values of neutrophils and lymphocytes. The sensitivity and specificity for the diagnosis of peritonitis of different analytical parameters were determined by ROC curves. RESULTS: A total of 398 patients were included (uncomplicated AA n=342 and AA with peritonitis n=56), with a mean age of 10.5±2.9 years. The NLR had an area under the curve (AUC) of 0.78, significantly higher than the determination of leukocytes (AUC 0.71, p=0.002) and of neutrophils (AUC 0.74, p=0.009). No differences were observed when compared to the determination of C-reactive protein (AUC 0.79, p=0.598). A cut-off point of NLR>8.75 was estimated with a sensitivity and specificity of 75.0 and 72.2% respectively. CONCLUSIONS: The NLR is a useful tool to predict the presence of peritonitis in AA, and could be considered an alternative to other higher cost determinations such as C-reactive protein.


INTRODUCCION: El índice neutrófilo-linfocito (INL) se ha postulado como marcador inflamatorio en distintas patologías abdominales como la apendicitis aguda (AA). Sin embargo, existen pocos estudios que determinen su asociación con el grado de severidad de la AA. Este es el primer estudio que analiza la utilidad del INL como factor predictor de peritonitis en la AA en niños. MATERIAL Y METODOS: Estudio observacional retrospectivo en pacientes intervenidos de AA durante los años 2017 y 2018. Se distribuyeron en dos grupos según el diagnóstico intraoperatorio (AA no complicada y AA con peritonitis). Se analizaron variables demográficas y analíticas. Se definió el INL como el cociente entre los valores absolutos de neutrófilos y linfocitos. Se determinó mediante curvas ROC la sensibilidad y especificidad para el diagnóstico de peritonitis de distintos parámetros analíticos. RESULTADOS: Se incluyeron un total de 398 pacientes (AA no complicada n= 342 y AA con peritonitis n=56), con una edad media de 10,5±2,9 años. El INL presentó un área bajo la curva (AUC) de 0,78, significativamente superior a la determinación de leucocitos (AUC 0,71; p=0,002) y de neutrófilos (AUC 0,74; p=0,009). No se observaron diferencias al compararlo con la determinación de la proteína C reactiva (AUC 0,79; p=0,598). Se estimó el punto de corte de INL>8,75 con una sensibilidad y especificidad de 75,0 y 72,2% respectivamente. CONCLUSION: El INL se postula como una herramienta útil para predecir la presencia de peritonitis en AA, y podría considerarse una alternativa a otras determinaciones de mayor coste como la proteína C reactiva.


Assuntos
Apendicite/sangue , Apendicite/complicações , Linfócitos , Neutrófilos , Peritonite/sangue , Peritonite/etiologia , Doença Aguda , Criança , Feminino , Humanos , Contagem de Leucócitos , Masculino , Valor Preditivo dos Testes , Estudos Retrospectivos
10.
Cir. pediátr ; 32(4): 185-189, oct. 2019. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-184107

RESUMO

Introducción. El índice neutrófilo-linfocito (INL) se ha postulado como marcador inflamatorio en distintas patologías abdominales como la apendicitis aguda (AA). Sin embargo, existen pocos estudios que determinen su asociación con el grado de severidad de la AA. Este es el primer estudio que analiza la utilidad del INL como factor predictor de peritonitis en la AA en niños. Material y métodos. Estudio observacional retrospectivo en pacientes intervenidos de AA durante los años 2017 y 2018. Se distribuyeron en dos grupos según el diagnóstico intraoperatorio (AA no complicada y AA con peritonitis). Se analizaron variables demográficas y analíticas. Se definió el INL como el cociente entre los valores absolutos de neutrófilos y linfocitos. Se determinó mediante curvas ROC la sensibilidad y especificidad para el diagnóstico de peritonitis de distintos parámetros analíticos. Resultados. Se incluyeron un total de 398 pacientes (AA no complicada n= 342 y AA con peritonitis n=56), con una edad media de 10,5±2,9 años. El INL presentó un área bajo la curva (AUC) de 0,78, significativamente superior a la determinación de leucocitos (AUC 0,71; p=0,002) y de neutrófilos (AUC 0,74; p=0,009). No se observaron diferencias al compararlo con la determinación de la proteína C reactiva (AUC 0,79; p=0,598). Se estimó el punto de corte de INL>8,75 con una sensibilidad y especificidad de 75,0 y 72,2% respectivamente. Conclusión. El INL se postula como una herramienta útil para predecir la presencia de peritonitis en AA, y podría considerarse una alternativa a otras determinaciones de mayor coste como la proteína C reactiva


Aim of the study. The neutrophilto-lymphocyte ratio (NLR) has been postulated as an inflammatory marker in several abdominal pathologies such as acute appendicitis (AA). However, there are few studies that determine its association with the degree of severity of AA. This is the first study that analyzes the usefulness of NLR as a predictor of peritonitis in children with AA. Methods. Retrospective observational study in patients treated of AA during the years 2017 and 2018. They were divided into two groups according to the intraoperative diagnosis (uncomplicated AA and AA with peritonitis). Demographic and analytical variables were analyzed. The NLR was defined as the quotient between the absolute values of neutrophils and lymphocytes. The sensitivity and specificity for the diagnosis of peritonitis of different analytical parameters were determined by ROC curves. Results. A total of 398 patients were included (uncomplicated AA n=342 and AA with peritonitis n=56), with a mean age of 10.5±2.9 years. The NLR had an area under the curve (AUC) of 0.78, significantly higher than the determination of leukocytes (AUC 0.71, p=0.002) and of neutrophils (AUC 0.74, p=0.009). No differences were observed when compared to the determination of C-reactive protein (AUC 0.79, p=0.598). A cut-off point of NLR>8.75 was estimated with a sensitivity and specificity of 75.0 and 72.2% respectively. Conclusions. The NLR is a useful tool to predict the presence of peritonitis in AA, and could be considered an alternative to other higher cost determinations such as C-reactive protein


Assuntos
Humanos , Masculino , Feminino , Criança , Apendicite/diagnóstico , Peritonite/diagnóstico , Linfócitos/fisiologia , Contagem de Leucócitos/métodos , Valor Preditivo dos Testes , Apendicite/sangue , Índice de Gravidade de Doença , Curva ROC , Estudos Retrospectivos
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